Advisers to the Food and Drug Administration meet Wednesday on GRAIL’s Galleri blood test, which looks for many cancers at once in adults 50 and older. A large British trial did not statistically cut late-stage cancers by its main pre-set goal, and no study has yet shown the test
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Wednesday, September 23 | ~5–7 min for Three to Know · Morning Wire · Updated 7am ET · Midday Wire · Updated 11am ET · Evening Wire · Updated 5pm ET
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MIDDAY WIRE
Updated 11am ET · unique pullsMEKELLE / ADDIS ABABA — Ethiopia’s Tigray regional government said Wednesday that its fighters have entered a “defensive war” against federal troops, hours after Tigrayan forces seized control of federally administered airports in the northern region, Reuters and AFP reported.
UNITED NATIONS — U.S. Secretary of State Marco Rubio met Russian Foreign Minister Sergey Lavrov in New York on Wednesday on the sidelines of the U.N. General Assembly, Anadolu Agency reported; the talks began without opening press remarks and continued behind closed doors.
WARSAW — A Russian military Mi-8 helicopter made a brief incursion into NATO member Poland’s airspace from the Russian exclave of Kaliningrad on Wednesday, the Polish Army Operational Command said, Reuters reported.
EVENING WIRE
Updated 5pm ET · unique pullsUNITED NATIONS — After a roughly 50-minute closed-door meeting with Russian Foreign Minister Sergey Lavrov, U.S. Secretary of State Marco Rubio told reporters that Ukraine and Russia have both voiced interest in a limited ceasefire covering grain and energy-related targets, Reuters reported.
UNITED NATIONS — Ukrainian President Volodymyr Zelenskiy urged world leaders Wednesday to keep choking Russia’s revenues, telling the U.N. General Assembly that “Russia’s revenues must remain a target,” the Associated Press reported.
UNITED NATIONS / TEHRAN — Iran’s Foreign Ministry said Wednesday it maintained its negotiating stance in unscheduled indirect talks with U.S. officials via Qatari mediators, demanding an end to the port blockade and release of frozen assets, the Associated Press reported.
UNITED NATIONS / JERUSALEM — Israeli Prime Minister Benjamin Netanyahu’s office on Wednesday called French President Emmanuel Macron’s U.N. claim that “Hamas has never struck in the West Bank” a “grotesque absurdity,” AFP and France 24 reported.
What we’re
watching next.
Not just more headlines.
What changes, and why it matters.
Health / Galleri
FDA advisers meet Wednesday on the Galleri multi-cancer blood test after the big trial missed its main goal — what the panel vote means for people who already buy the test.
Energy / Diesel
Whether U.S. diesel export-ban talk moves pump prices and futures off record prints.
Iran / Hormuz
Whether Tehran’s claim it could reopen Hormuz in seven days if Washington eases the blockade becomes real for shipping.
Poland / Airspace
Whether Polish DORSZ scrambles and brief Lublin–Rzeszów pauses become a standing pattern as Russian jet drones work Ukraine next to the border.
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